Cyclin D1 Gene Ablation Confers Neuroprotection in Traumatic Brain Injury

Cell cycle activation (CCA) is one of the principal secondary injury mechanisms following brain trauma, and it leads to neuronal cell death, microglial activation, and neurological dysfunction. Cyclin D1 (CD1) is a key modulator of CCA and is upregulated in neurons and microglia following traumatic...

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Hlavní autoři: Kabadi, Shruti V., Stoica, Bogdan A., Loane, David J., Byrnes, Kimberly R., Hanscom, Marie, Cabatbat, Rainier M., Tan, Ming T., Faden, Alan I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2012
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303105/
https://ncbi.nlm.nih.gov/pubmed/21895533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2011.1980
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