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Cyclin D1 Gene Ablation Confers Neuroprotection in Traumatic Brain Injury

Cell cycle activation (CCA) is one of the principal secondary injury mechanisms following brain trauma, and it leads to neuronal cell death, microglial activation, and neurological dysfunction. Cyclin D1 (CD1) is a key modulator of CCA and is upregulated in neurons and microglia following traumatic...

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Bibliografiske detaljer
Main Authors: Kabadi, Shruti V., Stoica, Bogdan A., Loane, David J., Byrnes, Kimberly R., Hanscom, Marie, Cabatbat, Rainier M., Tan, Ming T., Faden, Alan I.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303105/
https://ncbi.nlm.nih.gov/pubmed/21895533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2011.1980
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