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Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors.
The mechanism of action of macrophage colony-stimulating factor (M-CSF) in osteoclast development was examined in a co-culture system of mouse osteoblastic cells and spleen cells. In this co-culture, osteoclast-like multinucleated cells (MNCs) were formed within 6 d in response to 10 nM 1 alpha,25(O...
Gespeichert in:
| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
1993
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116179 |
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