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Vitamin D endocrine system and osteoclasts
Vitamin D was discovered as an anti-rachitic agent preventing a failure in bone mineralization, but it is now established that the active form of vitamin D(3) (1α,25(OH)(2)D(3)) induces bone resorption. Discovery of the receptor activator of nuclear factor -κB ligand (RANKL) uncovered the molecular...
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Formato: | Artigo |
Idioma: | Inglês |
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Nature Publishing Group
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944126/ https://ncbi.nlm.nih.gov/pubmed/24605212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2013.229 |
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