Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

We previously reported that osteoclast-like cells were formed in cocultures of a mouse marrow-derived stromal cell line (ST2) with mouse spleen cells in the presence of 1 alpha, 25-dihydroxyvitamin D3 and dexamethasone. In this study, we developed a new coculture system to determine the origin of os...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Udagawa, N, Takahashi, N, Akatsu, T, Tanaka, H, Sasaki, T, Nishihara, T, Koga, T, Martin, T J, Suda, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2169622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.7260
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