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PEA-15 potentiates H-Ras mediated epithelial cell transformation through Phospholipase D
The small GTPase H-Ras is a proto-oncogene that activates a variety of different pathways including the extracellular-signal-regulated kinase mitogen-activated protein kinase (ERK/MAPK) pathway. H-Ras is mutated in many human malignancies and these mutations cause the protein to be constitutively ac...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295902/ https://ncbi.nlm.nih.gov/pubmed/22105357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.514 |
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