PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma

ERK and RSK2 drive proliferation and invasion of many cancers. Phosphoprotein Enriched in Astrocytes 15 (PEA15) binds ERK and RSK2 and high PEA15 levels can impair ERK- and RSK2-dependent transcription. PEA15 expression also inversely correlates with cell motility and invasiveness. We therefore test...

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Main Authors: Gawecka, Joanna E., Geerts, Dirk, Koster, Jan, Caliva, Maisel J., Sulzmaier, Florian J., Opoku-Ansah, John, Wada, Randal K., Bachmann, André S., Ramos, Joe W.
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757132/
https://ncbi.nlm.nih.gov/pubmed/22213050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27415
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