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PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma
ERK and RSK2 drive proliferation and invasion of many cancers. Phosphoprotein Enriched in Astrocytes 15 (PEA15) binds ERK and RSK2 and high PEA15 levels can impair ERK- and RSK2-dependent transcription. PEA15 expression also inversely correlates with cell motility and invasiveness. We therefore test...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757132/ https://ncbi.nlm.nih.gov/pubmed/22213050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27415 |
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