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Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter
Abnormal ERK signaling is implicated in many human diseases including cancer. This signaling cascade is a good target for the therapy of certain malignancies because of its important role in regulating cell proliferation and survival. The small phosphoprotein PEA-15 is a potent regulator of the ERK...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442804/ https://ncbi.nlm.nih.gov/pubmed/22694972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.20021 |
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