RSK2 Protein Suppresses Integrin Activation and Fibronectin Matrix Assembly and Promotes Cell Migration

Modulation of integrin activation is important in many cellular functions including adhesion, migration, and assembly of the extracellular matrix. RSK2 functions downstream of Ras/Raf and promotes tumor cell motility and metastasis. We therefore investigated whether RSK2 affects integrin function. W...

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Autors principals: Gawecka, Joanna E., Young-Robbins, Shirley S., Sulzmaier, Florian J., Caliva, Maisel J., Heikkilä, Minna M., Matter, Michelle L., Ramos, Joe W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527930/
https://ncbi.nlm.nih.gov/pubmed/23118220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423046
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