ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches

Epithelial ovarian cancer (EOC) remains the most lethal gynecological malignancy in the United States. EZH2 silences gene expression through trimethylating lysine 27 on histone H3 (H3K27Me3). EZH2 is often overexpressed in EOC and has been suggested as a target for EOC intervention. However, EZH2 ta...

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Autori principali: Li, Hua, Bitler, Benjamin G., Vathipadiekal, Vinod, Maradeo, Marie E., Slifker, Michael, Creasy, Caretha L., Tummino, Peter J., Cairns, Paul, Birrer, Michael J., Zhang, Rugang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294119/
https://ncbi.nlm.nih.gov/pubmed/22144423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0414
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