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Targeting CARM1 in ovarian cancer with EZH2 and PARP inhibitors

Coactivator-associated arginine methyltransferase 1 (CARM1)-expressing high-grade serous ovarian cancers are characterized by poor prognosis and limited therapeutic options. Here we discuss a novel therapeutic strategy to target CARM1-expressing ovarian cancer based on a combination of poly (ADP-rib...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Principais autores: Karakashev, Sergey, Zhang, Rugang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469455/
https://ncbi.nlm.nih.gov/pubmed/32944622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1760675
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