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CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity
CARM1 is an arginine methyltransferase that asymmetrically dimethylates protein substrates on arginine residues. CARM1 is often overexpressed in human cancers. However, clinically applicable cancer therapeutic strategies based on CARM1 expression remain to be explored. Here, we report that EZH2 inhi...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5809368/ https://ncbi.nlm.nih.gov/pubmed/29434212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03031-3 |
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