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Epigenetic synthetic lethality in ovarian clear cell carcinoma: EZH2 and ARID1A mutations
The components of the Switch/Sucrose non-fermentable (SWI/SNF) complex are mutated in approximately 20% of human cancers. The A/T-rich interacting domain 1A (ARID1A) subunit has one of the highest mutation rates. Most notably, ARID1A is mutated in over 50% of ovarian clear cell carcinomas (OCCCs). W...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Oncol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845188/ https://ncbi.nlm.nih.gov/pubmed/27308548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1032476 |
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