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NF-YA underlies EZH2 upregulation and is essential for proliferation of human epithelial ovarian cancer cells
Epithelial ovarian cancer (EOC) accounts for the most gynecological malignancy-associated deaths in the United States. Enhancer of zeste homolog 2 (EZH2), which silences gene expression through generating trimethylation on lysine 27 residue of histone H3 (H3K27Me3), is often overexpressed in EOC and...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631279/ https://ncbi.nlm.nih.gov/pubmed/23360797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0661 |
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