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Homotropic Allosteric Regulation in Monomeric Mammalian Glucokinase
Glucokinase catalyzes the ATP-dependent phosphorylation of glucose, a chemical transformation that represents the rate-limiting step of glycolytic metabolism in the liver and pancreas. Glucokinase is a central regulator of glucose homeostasis as evidenced by its association with two disease states,...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294010/ https://ncbi.nlm.nih.gov/pubmed/22107947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.11.007 |
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