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Correction of Murine Bernard–Soulier Syndrome by Lentivirus-mediated Gene Therapy
Bernard–Soulier syndrome (BSS) is an inherited bleeding disorder caused by a defect in the platelet glycoprotein (GP) Ib-IX-V complex. The main treatment for BSS is platelet transfusion but it is often limited to severe bleeding episodes or surgical interventions due to the risk of alloimmunization....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293608/ https://ncbi.nlm.nih.gov/pubmed/22044935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.231 |
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