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Intravascular recovery of VWF and FVIII following intraperitoneal injection and differences from intravenous and subcutaneous injection in mice

Intravenous infusion studies in humans suggest that both VWF and FVIII remain intravascular in contrast to other coagulation proteins. We explored whether infusion of VWF and FVIII by either intraperitoneal (IP) or subcutaneous (SC) injection would result in efficient absorption of these large prote...

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Detalhes bibliográficos
Main Authors: Shi, Qizhen, Kuether, Erin L., Schroeder, Jocelyn A., Fahs, Scot A., Montgomery, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323668/
https://ncbi.nlm.nih.gov/pubmed/22221819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2516.2011.02735.x
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