Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model

Neurotrophic factors are integrally involved in the development of the nigrostriatal system and in combination with gene therapy, possess great therapeutic potential for Parkinson's disease (PD). Pleiotrophin (PTN) is involved in the development, maintenance, and repair of the nigrostriatal dop...

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Detalhes bibliográficos
Main Authors: Gombash, Sara E, Lipton, Jack W, Collier, Timothy J, Madhavan, Lalitha, Steece-Collier, Kathy, Cole-Strauss, Allyson, Terpstra, Brian T, Spieles-Engemann, Anne L, Daley, Brian F, Wohlgenant, Susan L, Thompson, Valerie B, Manfredsson, Fredric P, Mandel, Ronald J, Sortwell, Caryl E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293606/
https://ncbi.nlm.nih.gov/pubmed/22008908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.216
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