Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model

Neurotrophic factors are integrally involved in the development of the nigrostriatal system and in combination with gene therapy, possess great therapeutic potential for Parkinson's disease (PD). Pleiotrophin (PTN) is involved in the development, maintenance, and repair of the nigrostriatal dop...

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Bibliografiska uppgifter
Huvudupphovsmän: Gombash, Sara E, Lipton, Jack W, Collier, Timothy J, Madhavan, Lalitha, Steece-Collier, Kathy, Cole-Strauss, Allyson, Terpstra, Brian T, Spieles-Engemann, Anne L, Daley, Brian F, Wohlgenant, Susan L, Thompson, Valerie B, Manfredsson, Fredric P, Mandel, Ronald J, Sortwell, Caryl E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293606/
https://ncbi.nlm.nih.gov/pubmed/22008908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.216
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