Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model

Neurotrophic factors are integrally involved in the development of the nigrostriatal system and in combination with gene therapy, possess great therapeutic potential for Parkinson's disease (PD). Pleiotrophin (PTN) is involved in the development, maintenance, and repair of the nigrostriatal dop...

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Bibliografische gegevens
Hoofdauteurs: Gombash, Sara E, Lipton, Jack W, Collier, Timothy J, Madhavan, Lalitha, Steece-Collier, Kathy, Cole-Strauss, Allyson, Terpstra, Brian T, Spieles-Engemann, Anne L, Daley, Brian F, Wohlgenant, Susan L, Thompson, Valerie B, Manfredsson, Fredric P, Mandel, Ronald J, Sortwell, Caryl E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2012
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293606/
https://ncbi.nlm.nih.gov/pubmed/22008908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.216
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