Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model

Neurotrophic factors are integrally involved in the development of the nigrostriatal system and in combination with gene therapy, possess great therapeutic potential for Parkinson's disease (PD). Pleiotrophin (PTN) is involved in the development, maintenance, and repair of the nigrostriatal dop...

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Bibliografski detalji
Glavni autori: Gombash, Sara E, Lipton, Jack W, Collier, Timothy J, Madhavan, Lalitha, Steece-Collier, Kathy, Cole-Strauss, Allyson, Terpstra, Brian T, Spieles-Engemann, Anne L, Daley, Brian F, Wohlgenant, Susan L, Thompson, Valerie B, Manfredsson, Fredric P, Mandel, Ronald J, Sortwell, Caryl E
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293606/
https://ncbi.nlm.nih.gov/pubmed/22008908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.216
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