FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

In response to DNA damage or replication fork stress, the Fanconi anemia (FA) pathway is activated, leading to monoubiquitination of FancD2 and FancI and their co-localization in foci. Here we show that, in the chicken DT40 cell system, multiple alanine-substitution mutations in 6 conserved and clus...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ishiai, Masamichi, Kitao, Hiroyuki, Smogorzewska, Agata, Tomida, Junya, Kinomura, Aiko, Uchida, Emi, Saberi, Alihossein, Kinoshita, Eiji, Kinoshita-Kikuta, Emiko, Koike, Tohru, Tashiro, Satoshi, Elledge, Stephen J., Takata, Minoru
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293454/
https://ncbi.nlm.nih.gov/pubmed/18931676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1504
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares