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DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI
FANCI and FANCD2 form a complex, and play essential roles in the repair of interstrand DNA crosslinks (ICLs) by the Fanconi anemia (FA) pathway. FANCD2 is monoubiquitylated by the FA core complex, composed of 10 FA proteins including FANCL as the catalytic E3 subunit. FANCD2 monoubiquitylation can b...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378891/ https://ncbi.nlm.nih.gov/pubmed/22287633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks053 |
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