FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end

The FANCI-FANCD2 (I-D) complex is considered to work with RAD51 to protect the damaged DNA in the stalled replication fork. However, the means by which this DNA protection is accomplished have remained elusive. In the present study, we found that the I-D complex directly binds to RAD51, and stabiliz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Sato, Koichi, Shimomuki, Mayo, Katsuki, Yoko, Takahashi, Daisuke, Kobayashi, Wataru, Ishiai, Masamichi, Miyoshi, Hiroyuki, Takata, Minoru, Kurumizaka, Hitoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Genome Integrity, Repair and Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159555/
https://ncbi.nlm.nih.gov/pubmed/27694619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw876
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