FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end

The FANCI-FANCD2 (I-D) complex is considered to work with RAD51 to protect the damaged DNA in the stalled replication fork. However, the means by which this DNA protection is accomplished have remained elusive. In the present study, we found that the I-D complex directly binds to RAD51, and stabiliz...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Sato, Koichi, Shimomuki, Mayo, Katsuki, Yoko, Takahashi, Daisuke, Kobayashi, Wataru, Ishiai, Masamichi, Miyoshi, Hiroyuki, Takata, Minoru, Kurumizaka, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159555/
https://ncbi.nlm.nih.gov/pubmed/27694619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw876
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