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FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end

The FANCI-FANCD2 (I-D) complex is considered to work with RAD51 to protect the damaged DNA in the stalled replication fork. However, the means by which this DNA protection is accomplished have remained elusive. In the present study, we found that the I-D complex directly binds to RAD51, and stabiliz...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Sato, Koichi, Shimomuki, Mayo, Katsuki, Yoko, Takahashi, Daisuke, Kobayashi, Wataru, Ishiai, Masamichi, Miyoshi, Hiroyuki, Takata, Minoru, Kurumizaka, Hitoshi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159555/
https://ncbi.nlm.nih.gov/pubmed/27694619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw876
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