Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair

Fanconi anaemia (FA) is a rare hereditary disorder characterized by genomic instability and cancer susceptibility. A key FA protein, FANCD2, is targeted to chromatin with its partner, FANCI, and plays a critical role in DNA crosslink repair. However, the molecular function of chromatin-bound FANCD2-...

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Detalhes bibliográficos
Main Authors: Sato, Koichi, Ishiai, Masamichi, Toda, Kazue, Furukoshi, Satoshi, Osakabe, Akihisa, Tachiwana, Hiroaki, Takizawa, Yoshimasa, Kagawa, Wataru, Kitao, Hiroyuki, Dohmae, Naoshi, Obuse, Chikashi, Kimura, Hiroshi, Takata, Minoru, Kurumizaka, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433790/
https://ncbi.nlm.nih.gov/pubmed/22828868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.197
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