Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant

FANCD2 is a product of one of the genes associated with Fanconi anemia (FA), a rare recessive disease characterized by bone marrow failure, skeletal malformations, developmental defects, and cancer predisposition. FANCD2 forms a complex with FANCI (ID complex) and is monoubiquitinated, which facilit...

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發表在:PLoS One
Main Authors: Sato, Koichi, Ishiai, Masamichi, Takata, Minoru, Kurumizaka, Hitoshi
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260917/
https://ncbi.nlm.nih.gov/pubmed/25489943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114752
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