ΔF508 CFTR Pool in the Endoplasmic Reticulum Is Increased by Calnexin Overexpression

The most common cystic fibrosis transmembrane conductance regulator (CFTR) mutant in cystic fibrosis patients, ΔF508 CFTR, is retained in the endoplasmic reticulum (ER) and is consequently degraded by the ubiquitin-proteasome pathway known as ER-associated degradation (ERAD). Because the prolonged i...

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Publié dans:	Mol Biol Cell
Auteurs principaux:	Okiyoneda, Tsukasa, Harada, Kazutsune, Takeya, Motohiro, Yamahira, Kaori, Wada, Ikuo, Shuto, Tsuyoshi, Suico, Mary Ann, Hashimoto, Yasuaki, Kai, Hirofumi
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Cell Biology 2004
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14595111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-06-0379
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