Human lysosomal acid phosphatase is transported as a transmembrane protein to lysosomes in transfected baby hamster kidney cells.

BHK cells transfected with human lysosomal acid phosphatase (LAP) cDNA (CT29) expressed 70-fold higher enzyme activities of acid phosphatase than non-transfected BHK cells. The CT29-LAP was synthesized in BHK cells as a heterogeneously glycosylated precursor that was tightly membrane associated. Tra...

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Autors principals: Waheed, A, Gottschalk, S, Hille, A, Krentler, C, Pohlmann, R, Braulke, T, Hauser, H, Geuze, H, von Figura, K
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC457100/
https://ncbi.nlm.nih.gov/pubmed/3056714
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