Human lysosomal acid phosphatase is transported as a transmembrane protein to lysosomes in transfected baby hamster kidney cells.

BHK cells transfected with human lysosomal acid phosphatase (LAP) cDNA (CT29) expressed 70-fold higher enzyme activities of acid phosphatase than non-transfected BHK cells. The CT29-LAP was synthesized in BHK cells as a heterogeneously glycosylated precursor that was tightly membrane associated. Tra...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Waheed, A, Gottschalk, S, Hille, A, Krentler, C, Pohlmann, R, Braulke, T, Hauser, H, Geuze, H, von Figura, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC457100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3056714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03079.x
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