Human lysosomal acid phosphatase is transported as a transmembrane protein to lysosomes in transfected baby hamster kidney cells.

BHK cells transfected with human lysosomal acid phosphatase (LAP) cDNA (CT29) expressed 70-fold higher enzyme activities of acid phosphatase than non-transfected BHK cells. The CT29-LAP was synthesized in BHK cells as a heterogeneously glycosylated precursor that was tightly membrane associated. Tra...

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הוצא לאור ב:	EMBO J
Principais autores:	Waheed, A, Gottschalk, S, Hille, A, Krentler, C, Pohlmann, R, Braulke, T, Hauser, H, Geuze, H, von Figura, K
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Publishing Group 1988
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC457100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3056714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03079.x
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