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Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing

Previous estimates of the diversity of the mouse antibody repertoire have been based on fragmentary data owing to many technical limitations, in particular the many samples necessary to provide adequate coverage. Here, we used 5' coding end amplification of Igκ mRNAs from bone marrow, splenic a...

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Библиографические подробности
Главные авторы: Aoki-Ota, Miyo, Torkamani, Ali, Ota, Takayuki, Schork, Nicholas, Nemazee, David
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288532/
https://ncbi.nlm.nih.gov/pubmed/22287713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103484
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