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Regulation of the B cell receptor repertoire and self reactivity by BAFF
The cytokine BAFF promotes B lymphocyte survival and is overexpressed in individuals with systemic lupus erythematosus and Sjögren’s Syndrome. BAFF can rescue anergic autoreactive B cells from death, but only when competition from nonautoreactive B cells is lacking. Yet high BAFF levels promote auto...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263398/ https://ncbi.nlm.nih.gov/pubmed/20817867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002176 |
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