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Regulation of the B cell receptor repertoire and self reactivity by BAFF

The cytokine BAFF promotes B lymphocyte survival and is overexpressed in individuals with systemic lupus erythematosus and Sjögren’s Syndrome. BAFF can rescue anergic autoreactive B cells from death, but only when competition from nonautoreactive B cells is lacking. Yet high BAFF levels promote auto...

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Bibliografiset tiedot
Päätekijät: Ota, Miyo, Duong, Bao, Torkamani, Ali, Doyle, Colleen, Gavin, Amanda, Ota, Takayuki, Nemazee, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263398/
https://ncbi.nlm.nih.gov/pubmed/20817867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002176
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