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Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing

Previous estimates of the diversity of the mouse antibody repertoire have been based on fragmentary data owing to many technical limitations, in particular the many samples necessary to provide adequate coverage. Here, we used 5' coding end amplification of Igκ mRNAs from bone marrow, splenic a...

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Detalhes bibliográficos
Main Authors: Aoki-Ota, Miyo, Torkamani, Ali, Ota, Takayuki, Schork, Nicholas, Nemazee, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288532/
https://ncbi.nlm.nih.gov/pubmed/22287713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103484
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