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Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing

Previous estimates of the diversity of the mouse antibody repertoire have been based on fragmentary data owing to many technical limitations, in particular the many samples necessary to provide adequate coverage. Here, we used 5' coding end amplification of Igκ mRNAs from bone marrow, splenic a...

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Détails bibliographiques
Auteurs principaux: Aoki-Ota, Miyo, Torkamani, Ali, Ota, Takayuki, Schork, Nicholas, Nemazee, David
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288532/
https://ncbi.nlm.nih.gov/pubmed/22287713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103484
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