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Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing
Previous estimates of the diversity of the mouse antibody repertoire have been based on fragmentary data owing to many technical limitations, in particular the many samples necessary to provide adequate coverage. Here, we used 5' coding end amplification of Igκ mRNAs from bone marrow, splenic a...
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Auteurs principaux: | , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2012
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288532/ https://ncbi.nlm.nih.gov/pubmed/22287713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103484 |
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