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Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing

Previous estimates of the diversity of the mouse antibody repertoire have been based on fragmentary data owing to many technical limitations, in particular the many samples necessary to provide adequate coverage. Here, we used 5' coding end amplification of Igκ mRNAs from bone marrow, splenic a...

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Bibliografiske detaljer
Main Authors: Aoki-Ota, Miyo, Torkamani, Ali, Ota, Takayuki, Schork, Nicholas, Nemazee, David
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288532/
https://ncbi.nlm.nih.gov/pubmed/22287713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103484
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