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Sequence-dependent Variation in the Reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward Oxidation
The goal of this study was to define the effect of DNA sequence on the reactivity of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) toward oxidation. To this end, we developed a quadrupole/time-of-flight (QTOF) mass spectrometric method to quantify the reactivity of site-specifically modified ol...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288455/ https://ncbi.nlm.nih.gov/pubmed/22103813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200422g |
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