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8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine

The hydrogen-bonded guanine tetrad, or G-quartet has been implicated in a variety of biological roles, including the function of chromosome telomeres. Here effect of the hydroxylation of guanosine at the 8 position on the G-quartet formation was examined. Electrospray inonization mass (ESI-MS) spect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Iwahashi, Hideo
Format: Artigo
Sprache:Inglês
Veröffentlicht: the Society for Free Radical Research Japan 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613500/
https://ncbi.nlm.nih.gov/pubmed/19177189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.08-157
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