Peroxynitrite reaction products of 3′,5′-di-O-acetyl-8-oxo-7,8-dihydro-2′-deoxyguanosine
Of the DNA bases, peroxynitrite (ONOO(−)) is most reactive toward 2′-deoxyguanosine (dGuo), but even more reactive with 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo), requiring a 1,000-fold excess of dGuo to provide 50% protection against the reaction with 8-oxodGuo. Therefore, it seems reasonable...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11729 |
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