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Oxidation of 8-Oxo-7,8-dihydro-2′-deoxyguanosine by Oxyl Radicals Produced by Photolysis of Azo Compounds

Oxidative damage to 8-oxo-7,8-dihydroguanine (8-oxoG) bases initiated by photolysis of the water-soluble radical generator 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) has been investigated by laser kinetic spectroscopy. In neutral oxygenated aqueous solutions, 355 nm photolysis of AAPH init...

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Detalhes bibliográficos
Main Authors: Shao, Jie, Geacintov, Nicholas E., Shafirovich, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873103/
https://ncbi.nlm.nih.gov/pubmed/20408566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100022x
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