Protein Kinase C Regulation of 12-Lipoxygenase-Mediated Human Platelet Activation

Platelet activation is important in the regulation of hemostasis and thrombosis. Uncontrolled activation of platelets may lead to arterial thrombosis, which is a major cause of myocardial infarction and stroke. After activation, metabolism of arachidonic acid (AA) by 12-lipoxygenase (12-LOX) may pla...

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Main Authors: Yeung, Jennifer, Apopa, Patrick L., Vesci, Joanne, Kenyon, Victor, Rai, Ganesha, Jadhav, Ajit, Simeonov, Anton, Holman, Theodore R., Maloney, David J., Boutaud, Olivier, Holinstat, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286293/
https://ncbi.nlm.nih.gov/pubmed/22155783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.075630
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