Chargement en cours...
Cataract-Linked γD-Crystallin Mutants Have Weak Affinity to Lens Chaperones α-Crystallins
To test the hypothesis that α-crystallin chaperone activity plays a central role in maintenance of lens transparency, we investigated its interactions with γ-crystallin mutants that cause congenital cataract in mouse models. Although the two substitutions, I4F and V76D, stabilize a partially unfolde...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282170/ https://ncbi.nlm.nih.gov/pubmed/22289178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.019 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|