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Transgenic zebrafish models reveal distinct molecular mechanisms for cataract-linked αA-crystallin mutants
Mutations in the small heat shock proteins α-crystallins have been linked to autosomal dominant cataracts in humans. Extensive studies in vitro have revealed a spectrum of alterations to the structure and function of these proteins including shifts in the size of the oligomer, modulation of subunit...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6261105/ https://ncbi.nlm.nih.gov/pubmed/30475834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207540 |
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