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Species-specific structural and functional divergence of α-crystallins: zebrafish αBa- and rodent αA(ins)-crystallin encode activated chaperones

In addition to contributing to lens optical properties, the α-crystallins are small heat shock proteins that possess chaperone activity and are predicted to bind and sequester destabilized proteins to delay cataract formation. The current model of α-crystallin chaperone mechanism envisions a transit...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Koteiche, Hanane A., Claxton, Derek P., Mishra, Sanjay, McDonald, Ezelle T., Mchaourab, Hassane S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240591/
https://ncbi.nlm.nih.gov/pubmed/26378715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00678
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