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Specificity of αA-crystallin binding to destabilized mutants of βB1-crystallin.
To elucidate the structural and energetic basis of attractive protein interactions in the aging lens, we investigated the binding of destabilized mutants of βB1-crystallin to the lens chaperones, α-crystallins. We show that the mutations enhance the binding affinity to αA- but not αB-crystallin at p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2219212/ https://ncbi.nlm.nih.gov/pubmed/17449033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.04.005 |
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