Načítá se...

Cataract-Linked γD-Crystallin Mutants Have Weak Affinity to Lens Chaperones α-Crystallins

To test the hypothesis that α-crystallin chaperone activity plays a central role in maintenance of lens transparency, we investigated its interactions with γ-crystallin mutants that cause congenital cataract in mouse models. Although the two substitutions, I4F and V76D, stabilize a partially unfolde...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Mishra, Sanjay, Stein, Richard A., Mchaourab, Hassane S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282170/
https://ncbi.nlm.nih.gov/pubmed/22289178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.019
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!