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Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains
Neuronal cell death is an early pathological feature of diabetic retinopathy. We showed previously that insulin receptor signaling is diminished in retinas of animal models of diabetes and that downstream Akt signaling is involved in insulin-mediated retinal neuronal survival. Therefore, further und...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279305/ https://ncbi.nlm.nih.gov/pubmed/21205932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00641.2010 |
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