Cholesterol-enriched membrane microdomains are needed for insulin signaling and proliferation in hepatic cells

Hepatocyte proliferation during liver regeneration is a well-coordinated process regulated by the activation of several growth factor receptors, including the insulin receptor (IR). The IR can be localized in part to cholesterol-enriched membrane microdomains, but the role of such domains in insulin...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Fonseca, Matheus de Castro, França, Andressa, Florentino, Rodrigo Machado, Fonseca, Roberta Cristelli, Lima Filho, Antônio Carlos Melo, Vidigal, Paula Teixeira Vieira, Oliveira, André Gustavo, Dubuquoy, Laurent, Nathanson, Michael H., Leite, M. Fátima
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109708/
https://ncbi.nlm.nih.gov/pubmed/29471671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00008.2018
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