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The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly
The superoxide-producing phagocyte NADPH oxidase consists of a membrane-bound flavocytochrome b(558) complex, and cytosolic factors p47phox, p67phox and the small GTPase Rac, which translocate to the membrane to assemble the active complex following cell activation. We here show that insolubility of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC380990/ https://ncbi.nlm.nih.gov/pubmed/14765128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600066 |
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