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Regulation of NADPH Oxidase Activity in Phagocytes: RELATIONSHIP BETWEEN FAD/NADPH BINDING AND OXIDASE COMPLEX ASSEMBLY

The X(+)-linked chronic granulomatous disease (X(+)-CGD) variants are natural mutants characterized by defective NADPH oxidase activity but with normal Nox2 expression. According to the three-dimensional model of the cytosolic Nox2 domain, most of the X(+)-CGD mutations are located in/or close to th...

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Detalhes bibliográficos
Main Authors: Debeurme, Franck, Picciocchi, Antoine, Dagher, Marie-Claire, Grunwald, Didier, Beaumel, Sylvain, Fieschi, Franck, Stasia, Marie-José
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963400/
https://ncbi.nlm.nih.gov/pubmed/20724480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.151555
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