Down-regulation of NOX2 activity in phagocytes mediated by ATM-kinase dependent phosphorylation

NADPH oxidases (NOX) have many biological roles, but their regulation to control production of potentially toxic ROS molecules remains unclear. A previously identified insertion sequence of 21 residues (called NIS) influences NOX activity, and its predicted flexibility makes it a good candidate for...

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Dades bibliogràfiques
Publicat a:Free Radic Biol Med
Autors principals: Beaumel, Sylvain, Picciocchi, Antoine, Debeurme, Franck, Vives, Corinne, Hesse, Anne-Marie, Ferro, Myriam, Grunwald, Didier, Stieglitz, Heather, Thepchatri, Pahk, Smith, Susan M. E., Fieschi, Franck, Stasia, Marie José
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699957/
https://ncbi.nlm.nih.gov/pubmed/28916473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.09.007
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